GEO series
Prefrontal cortex bulk RNA-seq analysis of drug-treated PTEN KI heterozygous mice at P40
GSE319618
Mus musculus
Expression profiling by high throughput sequencing
30 samples
2026/07/28
GPL24247
Summary
Autism spectrum disorder (ASD) affects approximately 2.8% of the population and is characterized by substantial genetic heterogeneity. Bulk RNA sequencing was performed on prefrontal cortex tissue from PTEN KI heterozygous (HT) and wild-type (WT) mice. Animals were analyzed at postnatal day 40 (P40) following three weeks of treatment with fluoxetine or lithium. Both male and female mice were included. Dissected prefrontal cortex tissue was used for RNA extraction and sequencing.
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