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Single-cell V(D)J-seq of tumors from Eif3e cg1cre KO mice

GSE320525 Mus musculus Expression profiling by high throughput sequencing; Other 14 samples 2026/05/01 GPL24247
Summary
white nodules collected from tissues with evident tumor development in organs of cKO mice, such as liver, lung, and spleen were predominantly enriched with B cells or CD4+ T cells, and the lymphocytes within these tissues exhibited highly monoclonal enrichment (in one case, oligoclonal enrichment was observed), indicating that lymphocytes in the tumor tissues of cKO mice display characteristics of monoclonal expansion.
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