GEO series
ETV1 activates a rapid conduction transcriptional program in rodent and human cardiomyocytes [RNA-Seq]
GSE322182
Mus musculus
Expression profiling by high throughput sequencing
10 samples
2026/03/03
GPL17021
Summary
ETV1 (ER81) was identified as a highly enriched transcription factor in rapidly conducting atrial and His-Purkinje cardiomyocytes. Previous work has shown that ETV1 is a critical factor in determining fast conduction physiology in the heart. High-throughput sequencing project aims to uncover ETV1-dependent gene networks in cardiomyocytes, and transcriptomic changes in the left atrium under cardiac pressure overload. These results provide insight into the role of ETV1 in the establishment of rapid conduction zones in the heart.
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