Mouse heart RNA-seq in isoproterenol (ISO) injury model with or without polystyrene nanoplastics co-exposure
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Micro(nano)plastics in the Development of Myocardial Fibrosis: From Clinical Detection to Molecular MechanismCirculation research · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE322523_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1430366 and SRA study SRP680190. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9553608 Mouse heart RNA-seq ISO (A1)
- GSM9553609 Mouse heart RNA-seq ISO (A2)
- GSM9553610 Mouse heart RNA-seq ISO (A3)
- GSM9553611 Mouse heart RNA-seq ISO (A4)
- GSM9553612 Mouse heart RNA-seq ISO (A5)
- GSM9553613 Mouse heart RNA-seq ISO (A6)
- GSM9553614 Mouse heart RNA-seq ISO+100 nm PS (B1)
- GSM9553615 Mouse heart RNA-seq ISO+100 nm PS (B2)
- GSM9553616 Mouse heart RNA-seq ISO+100 nm PS (B3)
- GSM9553617 Mouse heart RNA-seq ISO+100 nm PS (B4)
- GSM9553618 Mouse heart RNA-seq ISO+100 nm PS (B5)
- GSM9553619 Mouse heart RNA-seq ISO+100 nm PS (B6)
- GSM9553620 Mouse heart RNA-seq ISO+1 µm PS (C1)
- GSM9553621 Mouse heart RNA-seq ISO+1 µm PS (C2)
- GSM9553622 Mouse heart RNA-seq ISO+1 µm PS (C3)
- GSM9553623 Mouse heart RNA-seq ISO+1 µm PS (C4)
- GSM9553624 Mouse heart RNA-seq ISO+1 µm PS (C5)
- GSM9553625 Mouse heart RNA-seq ISO+1 µm PS (C6)
- GSE274544 Single cell profiling reveals three endothelial to hematopoietic transitions with divergent isoform expression landscapes [scRNA-Seq] 1494 samples shares iso, rna-seq
- GSE319614 Bulk RNA-seq transcriptome profiling of hippocampus across 17 autism spectrum disorder mouse models 269 samples shares iso, rna-seq
- GSE291610 Splice isoform-perturbation coupled to single cell transcriptome profiling reveals functions of microexons in neurogenesis and autism-linked pathways [snRNA-Seq] 96 samples shares iso, rna-seq
- GSE309564 IFNg shapes macrophage inflammatory responses by STAT1 isoform-specific epigenetic and transcriptional mechanisms [RNA-Seq] 72 samples shares iso, rna-seq
- GSE272098 Elevated PKA activity at synapses and broad molecular disturbances in the striatum of Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder [snRNA-Seq] 61 samples shares iso, rna-seq
- GSE316703 Microbiota-Derived Isovalerate Ameliorates Sex-Specific Gut Barrier Dysfunction in Malnutrition [RNA-seq colon epithelium] 50 samples shares iso, rna-seq
- GSE296500 Crnic Institute Human Trisome Project - Trisomy 21 Model Atlas: PolyA RNA-seq from adult WT and Dp16 mouse liver tissue ± high fat diet 45 samples shares iso, rna-seq
- GSE291697 RNA-Seq experiments for isolated mice tissues in both WT and Mut mice 32 samples shares iso, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.