GEO series
Single Nuclei and Spatial Transcriptomic Datasets in Brain Metastases
GSE325196
Homo sapiens
Other; Expression profiling by high throughput sequencing
35 samples
2026/05/23
GPL24676
Summary
We performed single nuclei and spatial transcriptomic sequencing on a cohort of solid tumor human brain metastasis specimens resected at Duke University Medical Center from 1998 to 2022. This includes 23 single nuclei specimens, 12 Visium standard specimens, and 4 Xenium specimens. These samples encompass metastases from lung cancer, breast cancer, melanoma, and sarcoma primaries. Analysis of these data revealed novel tumor-microenvironment cell-cell interactions associated with patient survival.
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