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Transcriptome sequencing analysis of Cyp4f3b gene interference in human gallbladder carcinoma cells gbc-sd

GSE325472 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/03/25 Platform GPL24676
Summary
This study aimed to investigate the molecular mechanism underlying the effects of Cyp4f3b gene interference on the biological behaviors of human gallbladder carcinoma cells gbc-sd. Three replicate cell samples from each group (sh-NC control group and sh-Cyp4f3b interference group) were subjected to total RNA extraction and quality control, sequencing library construction and evaluation, RNA-seq sequencing and filtering, reference sequence alignment, gene expression level analysis, and differential expression analysis. Differentially expressed genes and significantly enriched signaling pathways were systematically identified to provide molecular evidence for clarifying the role of Cyp4f3b in gallbladder carcinogenesis and progression.
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Direct links to NCBI, no account and no request form: the whole study as GSE325472_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1440241 and SRA study SRP685357. Searching any of these in the dataset finder brings you back here.

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