Type I IFN Dynamics Orchestrate Protective ICAM1⁺ Neutrophil Heterogeneity as an Early Checkpoint for Survival in Lethal Viral Infection [day0 RNA-Seq]
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 10 × day0survived vs 10 × day0diedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE325974_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1442769 and SRA study SRP686630. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 2 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9618210 day0survived_1 day0survived
- GSM9618211 day0survived_2 day0survived
- GSM9618212 day0survived_3 day0survived
- GSM9618213 day0survived_4 day0survived
- GSM9618214 day0survived_5 day0survived
- GSM9618215 day0survived_6 day0survived
- GSM9618216 day0survived_7 day0survived
- GSM9618217 day0survived_8 day0survived
- GSM9618218 day0survived_9 day0survived
- GSM9618219 day0survived_10 day0survived
- GSM9618220 day0died_1 day0died
- GSM9618221 day0died_2 day0died
- GSM9618222 day0died_3 day0died
- GSM9618223 day0died_4 day0died
- GSM9618224 day0died_5 day0died
- GSM9618225 day0died_6 day0died
- GSM9618226 day0died_7 day0died
- GSM9618227 day0died_8 day0died
- GSM9618228 day0died_9 day0died
- GSM9618229 day0died_10 day0died
- GSE313732 Type I IFN Dynamics Orchestrate Protective ICAM1⁺ Neutrophil Heterogeneity as an Early Checkpoint for Survival in Lethal Viral Infection [RNA-Seq] 78 samples shares icam1, ifn, heterogeneity, orchestrate, protective, neutrophil, checkpoint
- GSE313167 Type I IFN Dynamics Orchestrate Protective ICAM1⁺ Neutrophil Heterogeneity as an Early Checkpoint for Survival in Lethal Viral Infection [ICAM1 RNAseq] 19 samples shares icam1, ifn, heterogeneity, orchestrate, protective, neutrophil, checkpoint
- GSE280164 An IFN/STAT1/CYBB Axis Defines Protective Plasmacytoid DC to Neutrophil Crosstalk in Aspergillus fumigatus Infected mice [RNA-seq] 24 samples shares ifn, protective, neutrophil
- GSE298786 Type I IFN impedes early bacterial control in TB-resistant and -susceptible mice and activates neutrophils to restrict lung macrophage-T cell interactions [RNA-seq] 70 samples shares ifn, neutrophil
- GSE283255 Distinct Vps34-orchestrated signaling processes dictate the transitional heterogeneity and functional adaptation of effector Treg cells [ATAC-seq2] 14 samples shares heterogeneity, orchestrate
- GSE283256 Distinct Vps34-orchestrated signaling processes dictate the transitional heterogeneity and functional adaptation of effector Treg cells [ATAC-seq1] 10 samples shares heterogeneity, orchestrate
- GSE326200 Absence of Clec1a in murine cDC1s decrease IFN responses to necrotic cells 237 samples shares ifn
- GSE309564 IFNg shapes macrophage inflammatory responses by STAT1 isoform-specific epigenetic and transcriptional mechanisms [RNA-Seq] 72 samples shares ifn
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.