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Mitochondrial transfer from astrocytes to endothelial cells reinforces redox homeostasis and barrier integrity in brain arteriovenous malformation

GSE326421 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2026/04/27 Platform GPL34290
Summary
Brain arteriovenous malformation (BAVM) is a high-flow vascular shunt that predisposes to intracranial hemorrhage and represents a leading cause of stroke in young adults. Somatic mutations in KRAS or BRAF drive endothelial dysfunction and lesion formation, yet the contribution of non-endothelial cells within the neuro-glial-vascular unit remains incompletely understood.
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Direct links to NCBI, no account and no request form: the whole study as GSE326421_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1445228 and SRA study SRP687825. Searching any of these in the dataset finder brings you back here.

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