GEO series
Transcriptomic profiling of primary mouse aortic smooth muscle cells treated with inflammatory macrophage-conditioned medium
GSE326694
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2026/06/03
GPL34290
Summary
Inflammatory cell infiltration is a hallmark of many vascular diseases, but the specific molecular mechanisms by which macrophage-derived signals influence smooth muscle cell (SMC) phenotype remain poorly defined. This study utilized bulk RNA sequencing to elucidate the transcriptomic shifts driven by the inflammatory macrophage secretome.
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Paper (PMID 41896892) ↗
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