Integrated single‑cell transcriptomic profiling of human peripheral blood mononuclear cells across diverse in vitro immune stimuli

Human peripheral blood mononuclear cells (PBMCs) from healthy donors were stimulated in vitro with a panel of commonly used immune stimuli and profiled using single‑cell RNA sequencing. The resulting dataset contains single-cell transcriptomic profiles of PBMCs across multiple donors and stimulation conditions. This resource enables comparative analysis of gene expression across immune cell populations and stimulation conditions and provides a reference for comparison with disease-associated immune signatures.