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Assay for Transposase-Accessible Chromatin With High-Throughput Sequencing in Mouse BMDMs Following CD74 Deficiency

GSE328037 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 6 samples Submitted 2026/04/19 Platform GPL21103
Summary
We employed ACAT-Seq technology to perform a genome-wide assessment of chromatin accessibility changes following CD74 knockout in mouse bone marrow-derived macrophages (BMDMs), with a focus on alterations in regulatory elements associated with aerobic glycolysis-related genes. On this basis, we further explored the potential molecular mechanisms by which CD74 regulates the aerobic glycolytic metabolic pathway in macrophages, including its impact on the accessibility of key transcription factor binding sites and the activity of associated signaling pathways.
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Also filed as BioProject PRJNA1453539 and SRA study SRP691829. Searching any of these in the dataset finder brings you back here.

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