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Early-life nutritional imbalance impairs colonic epithelial regeneration through gut microbiota dysbiosis and metabolic suppression

GSE328617 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/04/26 Platform GPL28330
Summary
Childhood malnutrition represents a major global health burden that extends beyond caloric deficiency to include dietary imbalance. The early-life gut microbiome functions as a dynamic ecosystem whose structure and metabolic output are intimately linked to host development, yet how nutritional imbalance disrupts this ecosystem and its integration with the host remains poorly understood.
Published in
Early life nutritional imbalance impairs colonic epithelial regeneration through gut microbiota dysbiosis and metabolic suppression
Zhuang Y, Huang Z, Liu S et al. · The ISME journal 2026 · PMID 42213059 · doi:10.1093/ismejo/wrag135
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Also filed as BioProject PRJNA1455991 and SRA study SRP693540. Searching any of these in the dataset finder brings you back here.

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