Glycine Receptor α2 Mediates Endothelium-dependent Vasodilation via Activation of eNOS Signaling
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 6 × WT vs 6 × KOGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE328949_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1457068 and SRA study SRP694292. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 2 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9694777 WT1 WT
- GSM9694778 WT2 WT
- GSM9694779 WT3 WT
- GSM9694780 WT4 WT
- GSM9694781 WT5 WT
- GSM9694782 WT6 WT
- GSM9694783 KO1 KO
- GSM9694784 KO2 KO
- GSM9694785 KO3 KO
- GSM9694786 KO4 KO
- GSM9694787 KO5 KO
- GSM9694788 KO6 KO
- GSE333586 Formylpeptide Receptor Activation Attenuates Renovascular Remodeling in Neurogenic Hypertension (Left Ventricle) 26 samples shares activation, receptor
- GSE333587 Formylpeptide Receptor Activation Attenuates Renovascular Remodeling in Neurogenic Hypertension (Kidney) 19 samples shares activation, receptor
- GSE267270 Synthetic trimeric Interleukin-6 receptor complexes with a STAT3 phosphorylation dominated activation profile 16 samples shares activation, receptor
- GSE293372 Coordinate tumor-antigen uptake and dendritic cell activation by chimeric antigen receptors. [RNA-seq] 12 samples shares activation, receptor
- GSE236129 Activation of RAS/MEK/ERK signaling drives biliary differentiation in primary liver cancer [112UE] 80 samples shares activation
- GSE306262 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [RNA-seq] 40 samples shares receptor
- GSE275408 Reactivation of mTOR signaling slows neurodegeneration in a lysosomal storage disease 24 samples shares activation
- GSE303657 R-spondin 2 suppresses hepatic steatosis via activation of AMPK-ACC signaling 12 samples shares activation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.