GEO series
Diurnal choroid plexus function in mice depends on sex, age, and amyloid-b status
GSE329540
Mus musculus
Expression profiling by high throughput sequencing
28 samples
2026/05/09
GPL24247
Summary
The adult choroid plexus (ChP) produces the majority of cerebrospinal fluid (CSF), yet little is known about the biological and physiological factors that regulate the ChP under healthy conditions. CSF physiology is regulated by sleep and/or time of day and alters with age and in Alzheimer’s disease (AD), where sleep and circadian disruption often co-occur. We compare the transcriptome from mouse ChP in three conditions (young, aged, aged with amyloid b (Ab) pathology) collected at day and night.
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