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Single-nuclei RNA-sequencing (snRNA-seq) of murine pancreatic tumors derived from the orthotopic transplantation of Smad4 WT or Smad4 KO pancreatic ductal adenocarcinoma (PDAC) KPC (i.e. KrasG12D; p53 mutant) organoids in C57BL/6J mice.

GSE329665 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/07/02 Platform GPL24247
Summary
We investigated the impact of SMAD4 loss in PDAC tumors from orthotopically grafted organoid-derived mouse models using snRNA-sequencing.
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Direct links to NCBI, no account and no request form: the whole study as GSE329665_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1460582 and SRA study SRP696503. Searching any of these in the dataset finder brings you back here.

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