Beta-hydroxybutyrate restores OXPHOS to reduce ischemia-induced AKI
RNA-seq (gene expression) · mouse · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 9 samples: 3 × Sham vs 3 × bIRI vs 3 × BHBNa_bIRIGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE329901_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1290348 and SRA study SRP600165. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 3 replicated groups read from 9 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9712905 Sham_1 Sham
- GSM9712906 Sham_2 Sham
- GSM9712907 Sham_3 Sham
- GSM9712908 bIRI_1 bIRI
- GSM9712909 bIRI_2 bIRI
- GSM9712910 bIRI_3 bIRI
- GSM9712911 BHBNa_bIRI_1 BHBNa_bIRI
- GSM9712912 BHBNa_bIRI_2 BHBNa_bIRI
- GSM9712913 BHBNa_bIRI_3 BHBNa_bIRI
- GSE263057 PARKIN is not required to sustain OXPHOS function in adult mammalian tissues 142 samples shares oxphos
- GSE310244 Dynamic Resilience: Stress Phenotypes and Their Impact on Opioid-Taking Behavior, Brain Activity, and Gene Expression 68 samples shares aki
- GSE282275 Adolescent circadian rhythm disruption increases reward and risk-taking 62 samples shares aki
- GSE278496 HiJAKing the hematopoietic system: a low-frequency JAK2V617F clone drives myeloproliferative neoplasm pathology 43 samples shares aki
- GSE268009 Strategic timing of contralateral nephrectomy after ischemic AKI prevents CKD by enhancing epithelial progenitor proliferation while attenuating polyploidization 41 samples shares aki
- GSE266396 Cx43-mediated mitochondrial transfer from MSCs mitigate oxidative stress-inflammation interplay in IRI-AKI via PGC1a activation 40 samples shares aki
- GSE263678 Time‑course analysis of cisplatin induced AKI in preclinical models: implications for testing different sources of MSCs 32 samples shares aki
- GSE220691 Kidney Single-Cell Atlas Reveals Macrophage Heterogeneity in Progression and Regression of Cisplatin Induced AKI. 22 samples shares aki
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.