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CHD8 haploinsufficiency impairs ventral progenitor proliferation and inhibitory neuronal maturation in human ventral forebrain organoids

GSE330233 Homo sapiens Expression profiling by high throughput sequencing 12 samples 2026/05/12 GPL24676
Summary
We performed bulk RNA-seq analysis of human ventral forebrain organoids to investigate transcriptomic changes associated with CHD8 heterozygous knockout. Sequencing data were generated from CHD8 heterozygous knockout samples and corresponding control samples.
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