Panax notoginseng -derived extracellular vesicles alleviate doxorubicin-induced cardiotoxicity by suppressing p53 activation
RNA-seq (gene expression) · mouse · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 9 samples: 9 × RNA-seq of heartGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Panax notoginseng-derived extracellular vesicles alleviate doxorubicin-induced cardiotoxicity by suppressing p53 activationPhytomedicine : international journal of phytotherapy and phytopharmacology · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE330352_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1463682 and SRA study SRP698655. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 1 replicated groups read from 9 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9724307 RNA-seq of heart_1 RNA-seq of heart
- GSM9724308 RNA-seq of heart_2 RNA-seq of heart
- GSM9724309 RNA-seq of heart_3 RNA-seq of heart
- GSM9724310 RNA-seq of heart_4 RNA-seq of heart
- GSM9724311 RNA-seq of heart_5 RNA-seq of heart
- GSM9724312 RNA-seq of heart_6 RNA-seq of heart
- GSM9724313 RNA-seq of heart_7 RNA-seq of heart
- GSM9724314 RNA-seq of heart_8 RNA-seq of heart
- GSM9724315 RNA-seq of heart_9 RNA-seq of heart
- GSE307421 Activation of CISD2 as a Protective Strategy against Doxorubicin-Induced Cardiotoxicity 24 samples shares doxorubicin-induced, cardiotoxicity, activation
- GSE327752 Human breast milk-derived extracellular vesicles alleviate Alzheimer’s disease phenotypes through delivering CD36 18 samples shares extracellular, alleviate, vesicles
- GSE313455 Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles which enhance plaque clearance by microglia [RNA-Seq] 10 samples shares extracellular, alleviate, vesicles
- GSE201969 In vivo self-assembly and targeted delivery of EGFR siRNA-encapsulating small extracellular vesicles to EGFR-positive cancer cells for NSCLC therapy 72 samples shares extracellular, vesicles
- GSE242731 Class switch recombination regulation by extracellular vesicles mediated intercellular epigenomic signaling 48 samples shares extracellular, vesicles
- GSE240538 A bone regenerative strategy based on extracellular vesicles transporting citrate for promoting biomineralization 37 samples shares extracellular, vesicles
- GSE240536 A bone regenerative strategy based on extracellular vesicles transporting citrate for promoting biomineralization [timepoint] 33 samples shares extracellular, vesicles
- GSE272476 Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells [RNA-seq] 30 samples shares extracellular, vesicles
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.