Transcriptomic data of the placenta from post-term mice caused by the absence of steroid hormone receptor coactivators

Parturition depends on precise communication between the mother and fetus.Our previous study demonstrated that wild-type mice carrying fetuses doubly deficient in steroid receptor coactivators (Src)-1 and Src-2 (Src-1/-2d/d) manifested a delay in parturition of 1–2 days, caused by a deficiency in surfactant protein A (SP-A) and platelet-activating factor (PAF) production by the fetal lungs. To investigate whether placental dysfunction contributes to this phenotype and identify placenta-derived parturition signals, the current study investigated alterations in gene expression in the placentas of Src-1/-2 double-knockout (dko) fetuses.