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RNA transcript changes in Itpr3 p.R2523C Effector Memory CD4+ T cells

GSE332595 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/05/21 Platform GPL34290
Summary
Mutations in inositol trisphosphate receptor type 3 (ITPR3) have been linked to immunodeficiency, including an expansion of effector memory (EM) CD4+ T cells within peripheral tissues. We developed a mouse model that genocopied a single allelic (p.R2524C) ITPR3 mutation found in humans.
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Also filed as BioProject PRJNA1468655 and SRA study SRP702394. Searching any of these in the dataset finder brings you back here.

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