Transcriptome profiling of ovaries in aged mice administered additional Samul-tang-associated compounds

Samul-tang (SM) is a traditional multi-ingredient treatment widely used in clinical practice for women's health and reproductive disorders. Despite its therapeutic benefits, the complexity of its mechanisms of action due to the combination of multiple compounds has limited its research integration into modern pharmacological science. To address this challenge, we identified 28 herbal compounds as major ingredients in SM and generated transcriptome data from the mice ovaries after administrating with individual ingredients. This dataset aims to provide insights into the mechanisms of action of SM and to aid in the identification of effective ingredient combinations.