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Targeting mitochondrial ROS-CK2-SET-PP2A pathway with ceria nanoparticles to reverse Tau pathology in APOEε4-associated Alzheimer’s disease [scRNA-seq]

GSE334035 Homo sapiens Expression profiling by high throughput sequencing 3 samples Submitted 2026/06/07 Platform GPL34281
Summary
In this study, we used triphenylphosphonium-conjugated ceria nanoparticles (Ceria-TPP) to target mitochondrial ROS in APOEε4 human iPSC-derived brain organoid, and profiled transcriptional changes via single-cell RNA-seq.
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Direct links to NCBI, no account and no request form: the whole study as GSE334035_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 3 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1473625 and SRA study SRP708258. Searching any of these in the dataset finder brings you back here.

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