← BioTransfer GEO Dataset Finder
GEO series

Transcriptome profiling of SCRMP knockout and control NCI-H69 small cell lung cancer cells

GSE337245 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/07/02 Platform GPL23227
Summary
This series contains RNA-seq data from NCI-H69 small cell lung cancer cells with CRISPR/Cas9-mediated SCRMP knockout and corresponding negative control cells. SCRMP is a microprotein encoded by MIR7-3HG that promotes cisplatin resistance and DNA damage repair in SCLC. The experiment was designed to identify gene expression changes caused by SCRMP depletion and to explore pathways involved in DNA damage repair and homologous recombination.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE337245_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1484555 and SRA study SRP714350. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.