Cannabidiol reverses microglial exhaustion in aged Gulf War Illness mice
RNA-seq (gene expression) · mouse · 22 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE338200_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1492717 and SRA study SRP716809. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 22 samples.
How we read this: 6 replicated groups read from 22 sample titles; they account for 22 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9869166 Veh: Ctrl mice_1 Ctrl mice
- GSM9869167 Veh: Ctrl mice_2 Ctrl mice
- GSM9869168 Veh: Ctrl mice_3 Ctrl mice
- GSM9869169 Veh: Ctrl mice_4 Ctrl mice
- GSM9869170 VehLPS: Ctrl mice with LPS_1 Ctrl mice with LPS
- GSM9869171 VehLPS: Ctrl mice with LPS_2 Ctrl mice with LPS
- GSM9869172 VehLPS: Ctrl mice with LPS_3 Ctrl mice with LPS
- GSM9869173 VehLPS: Ctrl mice with LPS_4 Ctrl mice with LPS
- GSM9869174 GW: GWI model mice_1 GWI model mice
- GSM9869175 GW: GWI model mice_2 GWI model mice
- GSM9869176 GW: GWI model mice_3 GWI model mice
- GSM9869177 GW: GWI model mice_4 GWI model mice
- GSM9869178 GWLPS: GWI model mice with LPS_1 GWI model mice with LPS
- GSM9869179 GWLPS: GWI model mice with LPS_2 GWI model mice with LPS
- GSM9869180 GWLPS: GWI model mice with LPS_3 GWI model mice with LPS
- GSM9869181 GWCBD30: GWI mice received CBD_1 GWI mice received CBD
- GSM9869182 GWCBD30: GWI mice received CBD_2 GWI mice received CBD
- GSM9869183 GWCBD30: GWI mice received CBD_3 GWI mice received CBD
- GSM9869184 GWCBD30LPS: GWI mice received CBD and with LPS 1 GWI mice received CBD a…
- GSM9869185 GWCBD30LPS: GWI mice received CBD and with LPS 2 GWI mice received CBD a…
- GSM9869186 GWCBD30LPS: GWI mice received CBD and with LPS 3 GWI mice received CBD a…
- GSM9869187 GWCBD30LPS: GWI mice received CBD and with LPS 4 GWI mice received CBD a…
- GSE254229 ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice 141 samples shares microglial, aged
- GSE254217 ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits. [in vitro_Microglia] 59 samples shares microglial, aged
- GSE290810 ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits [FACS_SpinalCord_Microglia & LPS_Brain_SpinalCord] 35 samples shares microglial, aged
- GSE254227 ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits. [FACS_Brain_Microglia] 35 samples shares microglial, aged
- GSE334769 Immunogen-Sponge Hydrogel Reverses TIM-3–Mediated Dendritic-Cell Exhaustion in Alveolar Echinococcosis 12 samples shares exhaustion, reverses
- GSE327428 GPR34 regulation of disease-associated microglial states in mice 96 samples shares microglial
- GSE307255 HDL-mimetic peptide treatment reverses APOE4-induced transcriptomic and lipidomic alterations in the brain of humanized APOE mice 32 samples shares reverses
- GSE320562 Immune checkpoint LAG-3 governs stage-dependent and disease-associated microglial modules in ALS model mice 32 samples shares microglial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.