GEO series
Transcriptomic profiling reveals IGF2BP1-mediated gene regulation and Helicobacter pylori-induced transcriptional reprogramming in gastric epithelial cells
GSE338493
Homo sapiens
Expression profiling by high throughput sequencing
11 samples
2026/07/29
GPL24676
Summary
Helicobacter pylori infection induces persistent transcriptional reprogramming in gastric epithelial cells. To identify downstream pathways regulated by IGF2BP1, RNA sequencing was performed in GES-1 cells with IGF2BP1 overexpression and H. pylori infection. Integrated analysis identified overlapping transcriptional programs associated with oxidative stress regulation and ferroptosis-related pathways.
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