Taxus cuspidata extract attenuates allergic airway inflammation, and its constituent taxinine targets the IL-17/TNF program in mast cells
RNA-seq (gene expression) · mouse · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 9 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE339137_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1497754 and SRA study SRP719504. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 9 more — browse all 9 samples with per-sample file links →
- GSE247462 An enriched circulating extracellular vesicle microRNA, miR-451a, attenuates the RORγt expression in T cells in secondary lymphoid tissues, thereby ameliorating IL-17A-mediated allergic responses 12 samples shares il-17, attenuates, allergic
- GSE334847 Hypoxic preconditioning attenuates renal ischemia–reperfusion injury by suppressing the IL-17A/IL-17RA/TRAF6 inflammatory axis 12 samples shares il-17, attenuates
- GSE325101 Ginsenoside Rg3 attenuates allergic asthma in mice via transcriptomics 15 samples shares attenuates, allergic
- GSE339436 CD97/ADGRE5 attenuates the induction of adaptive type 2 immune responses in allergic asthma 8 samples shares attenuates, allergic
- GSE239946 Signatures of IL1b, IL6 and TNFa in immune cell-types 209 samples shares tnf
- GSE75111 Single-cell transcriptional profiling of Th17 cells, differentiated in vitro for 48h [TGFB1_IL6-48h-IL-17A/GFP+] 151 samples shares il-17
- GSE232746 The GPR84 molecule is a mediator of a subpopulation of retinal microglia that promote TNF/IL-1α expression via the rho-ROCK pathway after optic nerve injury II 144 samples shares tnf
- GSE318351 IL1A enhances TNF-induced retinal ganglion cell death 109 samples shares tnf
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.