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Identification of Proteins Binding Coding and Non-coding Human RNAs using Protein Microarrays

GSE34794 Homo sapiens Other 20 samples Submitted 2012/10/10 Platform GPL13669
Summary
We describe a refined approach to identify new human RNA-protein interactions. In vitro transcribed labeled RNA is bound to ~9,400 human recombinant proteins spotted on protein microarrays. This approach identified 137 RNA-protein interactions for 10 human coding and non-coding RNAs, including an interaction between Staufen 1 protein and TP53 mRNA that promoted the latter’s stability. RNA hybridization to protein microarrays allows rapid identification of human RNA-protein interactions on a large scale.
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Also filed as BioProject PRJNA151039. Searching any of these in the dataset finder brings you back here.

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