SChLAP-1, a long non-coding RNA, antagonizes the SWI/SNF complex and coordinates aggressive prostate cancer.
Expression microarray · human · 28 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Topic
- Prostate cancerThis series is part of our curated briefing on it.
- Samples
- 28 samples: 12 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE40386_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA173819. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 28 samples.
How we read this: 12 replicated groups read from 28 sample titles; they account for 28 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM992631 22Rv1 siRNA-H Replicate 1 22Rv1 siRNA-H
- GSM992632 22Rv1 siRNA-H Replicate 2 22Rv1 siRNA-H
- GSM992633 22Rv1 siRNA-H Replicate 3 22Rv1 siRNA-H
- GSM992634 22Rv1 siRNA-J Replicate 1 22Rv1 siRNA-J
- GSM992635 22Rv1 siRNA-J Replicate 2 22Rv1 siRNA-J
- GSM992636 22Rv1 siRNA-J Replicate 3 22Rv1 siRNA-J
- GSM992637 LNCaP siRNA-H Replicate 1 LNCaP siRNA-H
- GSM992638 LNCaP siRNA-H Replicate 2 LNCaP siRNA-H
- GSM992639 LNCaP siRNA-H Replicate 3 LNCaP siRNA-H
- GSM992640 LNCaP siRNA-J Replicate 1 LNCaP siRNA-J
- GSM992641 LNCaP siRNA-J Replicate 2 LNCaP siRNA-J
- GSM992642 LNCaP siRNA-J Replicate 3 LNCaP siRNA-J
- GSM992643 22RV1 SMARCB1 siRNA-1 22RV1 SMARCB1 siRNA
- GSM992644 22RV1 SMARCB1 siRNA-2 22RV1 SMARCB1 siRNA
- GSM992645 22RV1 SMARCA4 siRNA-1 22RV1 SMARCA4 siRNA
- GSM992646 22RV1 SMARCA4 siRNA-2 22RV1 SMARCA4 siRNA
- GSM992647 22RV1 SMARCA2 siRNA-1 22RV1 SMARCA2 siRNA
- GSM992648 22RV1 SMARCA2 siRNA-2 22RV1 SMARCA2 siRNA
- GSM992649 LNCaP SMARCB1 siRNA-1 LNCaP SMARCB1 siRNA
- GSM992650 LNCaP SMARCB1 siRNA-2 LNCaP SMARCB1 siRNA
- GSM992651 LNCaP SMARCA4 siRNA-1 LNCaP SMARCA4 siRNA
- GSM992652 LNCaP SMARCA4 siRNA-2 LNCaP SMARCA4 siRNA
- GSM992653 LNCaP SMARCA2 siRNA-1 LNCaP SMARCA2 siRNA
- GSM992654 LNCaP SMARCA2 siRNA-2 LNCaP SMARCA2 siRNA
- GSM992655 RWPE SChLAP1 Isoform1 Replicate 1 RWPE SChLAP1 Isoform1
- GSM992656 RWPE SChLAP1 Isoform2 Replicate 1 RWPE SChLAP1 Isoform2
- GSM992657 RWPE SChLAP1 Isoform1 Replicate 2 RWPE SChLAP1 Isoform1
- GSM992658 RWPE SChLAP1 Isoform2 Replicate 2 RWPE SChLAP1 Isoform2
- GSE115501 RNA sequencing on circulating tumor cells from prostate cancer patients 136 samples same disease briefing · shares prostate
- GSE222467 The RNA binding proteins LARP4A and LARP4B promote tumour growth and metastasis in prostate cancer and osteosarcoma 12 samples same disease briefing · shares prostate
- GSE300947 A novel six-biomarker panel identified from male breast cancer-associated fibroblasts demonstrates prognostic power for prostate tumors 6 samples same disease briefing · shares prostate
- GSE120181 Human prostate cancer cell line, 22Rv1: Control vs. luteolin treatment 2 samples same disease briefing · shares prostate
- GSE71008 Plasma extracellular RNA profiles in healthy and cancer patients 192 samples same disease briefing
- GSE242541 ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity 12 samples same disease briefing
- GSE313838 Androgen receptor-negative prostate cancer is vulnerable to SWI/SNF-targeting degrader molecules 32 samples shares swi, snf, prostate
- GSE262093 SWI/SNF Chromatin Remodeling Complex Orchestrates Sequential Binding of Key Transcription Factors in B Cells and Restricts Aggressive Lymphoma [human ChIP-seq] 14 samples shares swi, snf, aggressive
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.