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Expression data from Adriamycin-treated Emu-myc; Suv39h1-/- B-cell lymphoma

GSE44355 Mus musculus Expression profiling by array 10 samples Submitted 2013/07/04 Platform GPL1261
Summary
Oncogene-induced senescence (OIS), a terminal cell cycle block countering (pre)neoplastic lesions, is characterised on the molecular level by trimethylated histone H3 lysine 9 (h3K9me3), a transcriptionally repressive chromatin mark linked to silencing of S-phase-promoting genes. Whether H3K9-governed chromatin remodelling influences anticancer treatment-induced senescence (TIS) and whether functional control of this mark impacts on treatment outcome is not known. We used global gene expression profiling by microarrays to gain insight into the molecular responses of Emu-myc; Suv39h1-/- B-cell lymphoma cells to senescence-inducing anticancer agent Adriamycin (ADR).
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Also filed as BioProject PRJNA189547. Searching any of these in the dataset finder brings you back here.

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