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Esophageal Cancer Project

GSE54995 Homo sapiens Genome variation profiling by genome tiling array 123 samples Submitted 2014/03/11 Platform GPL15436Platform GPL8736
Summary
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC). Currently, there are limited clinical approaches for early diagnosis and treatment for ESCC, resulting in a 10% 5-year survival rate for the patients. Meanwhile, the full repertoire of genomic events leading to the pathogenesis of ESCC remains unclear. Here we show a comprehensive genomic analysis in 158 ESCC cases, as part of the International Cancer Genome Consortium (ICGC) Research Projects (http://icgc.org/icgc/cgp/72/371/1001734). We conducted whole-genome sequencing in 17 ESCC cases and whole-exome sequencing in 71 cases, of which 53 cases and additional 70 ESCC cases were subjected to array comparative genomic hybridization (a-CGH) analysis.
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Direct links to NCBI, no account and no request form: the whole study as GSE54995_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 123 samples.

Also filed as BioProject PRJNA238218. Searching any of these in the dataset finder brings you back here.

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