Variant PRC1 complex dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 41 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 41 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE55698_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA240568 and SRA study SRP033245. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 41 more — browse all 41 samples with per-sample file links →
- GSE216807 Polycomb Repressive Complexes occupancy reveals PRC2- independent PRC1 critical role in the control of limb development [ChIP-seq] 19 samples shares prc1, prc2, dependent, polycomb
- GSE305054 Mapping early PRC2 nucleation sites upon Suz12 reintroduction reveals features of de novo Polycomb recruitment 18 samples shares prc2, recruitment, polycomb
- GSE249882 PRC1 and PRC2 proximal interactome in mouse embryonic stem cells [ChIP-Seq] 47 samples shares prc1, prc2
- GSE186579 Profiling of PRC1 and PRC2 occupancy reveals the preponderant role of PRC1 in regulating the limb development program 24 samples shares prc1, prc2
- GSE287032 H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation [ChIP-seq] 20 samples shares prc1, h2a
- GSE247019 Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch 134 samples shares h2a, polycomb
- GSE272603 DNA glycosylases Ogg1 and Mutyh mediate gene expression of PRC2 targets important for memory formation 128 samples shares prc2, formation
- GSE297309 SKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced gene [CUT&Tag] 108 samples shares prc2, polycomb
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.