GEO series

Pseudouridine profiling reveals widespread regulated mRNA pseudouridylation in yeast and human cells

GSE58200 Homo sapiens; Saccharomyces cerevisiae Expression profiling by high throughput sequencing; Other 109 samples Submitted 2014/09/05 Platform GPL11154Platform GPL13821

Summary

We report the development of Pseudo-Seq, a sequencing based technique for identification of pseuoduridine (Ψ) modifications within RNA. We performed Pseudo-Seq on S. cerevisiae and HeLa cells and find the first evidence for pseusouridylation of endogenous mRNAs.

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Direct links to NCBI, no account and no request form: the whole study as GSE58200_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 109 samples. Raw sequencing reads are also available from ENA.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗ Raw reads on ENA ↗

Also filed as BioProject PRJNA251554 and SRA study SRP042670. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 25192136) ↗

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