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Copy number profile of human prostate cancer organoid lines using Agilent 1M aCGH platform

GSE60612 Homo sapiens Genome variation profiling by genome tiling array 7 samples Submitted 2014/09/09 Platform GPL8737
Summary
Advanced prostate cancer is a highly heterogenous disease with few in vitro models. We report generation of seven novel 3D organoid lines of patient-derived prostate cancer. We determine the copy number alterations of these lines using array CGH. They contain may classic alterations of prostate cancer such as lost of the short arm of chromosome 8 and gain of the long arm of chromosome 8. In addition, we found homozygous deleteion of tumor suppressor PTEN and CHD1 as well as the TMPRSS2-ERG interstitial deletion.
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Also filed as BioProject PRJNA258649. Searching any of these in the dataset finder brings you back here.

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