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Delineating Tumor-infiltrating Antigen Presenting Cell populations

GSE61462 Mus musculus Expression profiling by high throughput sequencing 12 samples Submitted 2014/11/10 Platform GPL17021
Summary
The goal of this study is to compare tumor-infiltrating antigen presenting cell populations by global transcriptome profiling (RNA-seq) to help further delineate sub-populations of infiltrating myeloid cells in tumor. Methods: Four tumor antigen presenting cell populations were sorted from digested B78chOVA (melanoma variant) tumors in biological triplicate Results: RNA was extracted from the 4 groups (n=3 per group) and prepared for RNAseq. Sequencing yielded ~405 million reads with an average read depth of 33.7 million reads/sample. Reads were then aligned to the mouse genome (UCSC mm10) and those that mapped uniquely to known mRNAs were used to assess differential expression.
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Direct links to NCBI, no account and no request form: the whole study as GSE61462_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 12 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA261162 and SRA study SRP047171. Searching any of these in the dataset finder brings you back here.

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