← BioTransfer GEO Dataset Finder
GEO series

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

GSE77930 Homo sapiens Genome variation profiling by array; Expression profiling by array 320 samples Submitted 2016/02/16 Platform GPL15659Platform GPL21289
Summary
Tumor heterogeneity may reduce the efficacy of molecularly guided systemic therapy for cancers that have metastasized. To determine whether the genomic alterations in a single metastasis provide a reasonable assessment of the major oncogenic drivers of other dispersed metastases in an individual, we analyzed multiple tumors from men with disseminated prostate cancer through whole-exome sequencing, array comparative genomic hybridization (CGH) and RNA transcript profiling, and we compared the genomic diversity within and between individuals.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE77930_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 320 samples.

Also filed as BioProject PRJNA312246. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 320 more — browse all 320 samples with per-sample file links →

Similar datasets

Search all human datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.