GEO series

Expression data of GFP-neg and GFP-high cells isolated from mouse SCLC tumors using a GFP reporter for Hes1 expression

GSE81170 Mus musculus Expression profiling by array 6 samples Submitted 2017/04/21 Platform GPL16570

Summary

Small cell lung cancer (SCLC) tumors harbor two subsets of cells that are defined by low (or undetectable) or high expression of Hes1, which is a common downstream target of the Notch signaling pathway. To better understand the role of the Notch pathway in SCLC tumor heterogeneity, we first isolated cells from these two populations using a GFP-reporter allele for Hes1 expression. We then used microarrays to identify the gene expression differences between these two groups.

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Direct links to NCBI, no account and no request form: the whole study as GSE81170_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA320772. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 28489825) ↗

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