Gene expression analysis of parental cell lines and cell lines with acquired resistance to compound 3 (C03) and compound 7 (C07).
RNA-seq (gene expression) · human · 6 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 6 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE84875_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA335411 and SRA study SRP079924. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 6 more — browse all 6 samples with per-sample file links →
- GSE342640 Insulin resistance is associated with mammary mitochondrial dysfunction at the onset of human lactation 159 samples shares resistance
- GSE266389 Suppressing Aberrant Hedgehog Pathway and Overcoming Resistance to Smoothened Antagonists via Targeting Super-enhancer-driven Transcriptional Dependencies [RNA-seq] 60 samples shares resistance
- GSE274229 Evolution of myeloid-mediated immunotherapy resistance in prostate cancer 52 samples shares resistance
- GSE224478 ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution 51 samples shares resistance
- GSE294216 Resistance to the KRASG12D Inhibitor MRTX1133 is Associated with Aberrant Histone Acetylation and Increased Sensitivity to BET Inhibition 36 samples shares resistance
- GSE312638 Catestatin impedes melanoma progression and drug resistance by reprogramming oncogenic signaling pathways 22 samples shares resistance
- GSE251936 Circumventing Resistance within the Ewing Sarcoma Microenvironment by Anti-MCAM Chimeric Antigen Receptor Modified Ex-vivo Expanded Natural Killer Cells Combinatorial Therapy 22 samples shares resistance
- GSE224475 ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution (human+murine organoids subset) 21 samples shares resistance
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.