CRISPRi-based genome-scale identification of functional long non-coding RNA loci in human cells

Direct links to NCBI, no account and no request form: the whole study as GSE85011_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 112 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA335860 and SRA study SRP080367. Searching any of these in the dataset finder brings you back here.

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• GSE261284 Bioinformatics and single-cell CRISPRi-based screen reveals effector genes and implicates multi-tissue etiology for BMD 53 samples
• GSE146585 Functional genomics assays, including ChIP-seq, ATAC-seq, RNA-seq, GRO-seq, and in situ Hi-C, in the context of replicative senescence 223 samples
• GSE145327 Loss of extreme long-range enhancers in human neural crest drives a craniofacial disorder 80 samples
• GSE333877 Epigenetic landscape, key transcriptional regulators, and in vivo identification of human Tr1 cells 72 samples
• GSE267646 Novel Long Noncoding RNA HEAT4 Affects Monocyte Subtypes, Reducing Inflammation and Promoting Vascular Healing 53 samples
• GSE206078 ZNF512B Safeguards Genome Integrity at Regulatory Regions to Repress SASP and Inflammation 37 samples
• GSE287825 The METTL3-YTHDC1 axis mediates architectural RNA m6A modification to modulate the integrity of chromatin TADs in MLLr+ AML genome 36 samples
• GSE261033 Epigenetic landscape, key transcriptional regulators, and in vivo identification of human Tr1 cells [scMultiome] 28 samples

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