The Long Non-coding RNA Lnc-RAINY Regulates Genes Involved in Radiation Susceptibility Through DNA:DNA:RNA triplex-forming Interactions and has Tumor Therapeutic Potential in Non-small Cell Lung Cancers [ATAC-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 16 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 16 samples: 16 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Lnc-RAINY regulates genes involved in radiation susceptibility through DNA:DNA:RNA triplex-forming interactions and has tumor therapeutic potential in lung cancersNon-coding RNA research · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE274484_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1146490 and SRA study SRP525463. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 16 sample titles: 16 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8449981 H460 siCtrl NR ATAC-seq A
- GSM8449982 H460 siCtrl 8gy ATAC-seq A
- GSM8449983 H460 siPool NR ATAC-seq A
- GSM8449984 H460 siPool 8gy ATAC-seq A
- GSM8449985 H460 siCtrl NR ATAC-seq B
- GSM8449986 H460 siCtrl 8gy ATAC-seq B
- GSM8449987 H460 siPool NR ATAC-seq B
- GSM8449988 H460 siPool 8gy ATAC-seq B
- GSM8449989 H820 siCtrl NR ATAC-seq A
- GSM8449990 H820 siCtrl 8gy ATAC-seq A
- GSM8449991 H820 siPool NR ATAC-seq A
- GSM8449992 H820 siPool 8gy ATAC-seq A
- GSM8449993 H820 siCtrl NR ATAC-seq B
- GSM8449994 H820 siCtrl 8gy ATAC-seq B
- GSM8449995 H820 siPool NR ATAC-seq B
- GSM8449996 H820 siPool 8gy ATAC-seq B
- GSE268177 Modulating alternative splicing of MECP2: A potential therapeutic strategy for Rett syndrome 93 samples shares therapeutic, potential
- GSE273036 Multi-Omics Analysis and Molecular Subtypes Provide Potential Therapeutic Implications in Fumarate Hydratase-deficient Renal Cell Carcinoma 93 samples shares therapeutic, potential
- GSE335924 RNA-seq Identifies FOS as a Potential Therapeutic Target Activating Neural Stem Cells via miR-21/SOX2 Pathway in Hypertensive Intracerebral Hemorrhage 53 samples shares therapeutic, potential
- GSE268953 Cellular senescence in skeletal muscle aging: new mechanisms and therapeutic potential for sarcopenia [snMultiome_ATAC+GEX] 20 samples shares therapeutic, potential
- GSE245935 Chemo-senolytic therapeutic potential against angiosarcoma 13 samples shares therapeutic, potential
- GSE217531 Exploring the potential mechanism of artesunate in intervening with glioma cells with distinct therapeutic effects on the basis of transcriptome sequencing and network pharmacology 12 samples shares therapeutic, potential
- GSE281464 Dissecting Non-Coding GWAS Loci with High-Resolution 3D Chromatin Interactions Reveals Causal Genes with Relevance to Heart Failure [Perturb-seq] 7 samples shares interactions, non-coding
- GSE271752 Macromolecular interactions dictate Polycomb-mediated epigenetic repression [ChIP-seq] 194 samples shares interactions
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.