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Expression anaylsis of human mesenchymal and endothelial cells

GSE86885 Homo sapiens (human) Expression microarray 48 samples Submitted 2017/09/06 Platform GPL10558
At a glance

Expression microarray · human · 48 samples

What it is
Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
Organism
Homo sapiens (human)
Samples
48 samples: 9 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed expression table (series matrix) and the array files, from NCBI.
Summary (written by the submitters)
Analysis of differences in gene expression between different cell types of the vascular niche. Looking for candidates, that could potentially be up-or downregualted in the different cell types
This dataset
Download · which file do I need?

Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need.

All supplementary files ↗
3 · The original raw files

Whole study · RAW.tar

Everything the authors deposited as one archive (GSE86885_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.

What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.

Also filed as BioProject PRJNA342824. Searching any of these in the dataset finder brings you back here.

Study design
9 conditions, mostly in duplicate
stromal derived_mesenchymal stem cell_p2 ×7 dermal_fibroblast_p4 ×3 pancreas_pericyte_p4 ×2 pancreas_pericyte_p8 ×2 muscle_pericyte_p8 ×2 muscle_pericyte_p2 ×2 lung_pericyte_p4 ×2 dermal_fibroblast_p2 ×2 +25 more

Supports a between-group comparison across 24 samples.

How we read this: 9 replicated groups read from 48 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

+ 8 more — browse all 48 samples with per-sample file links →

Datasets on a similar topic

Search all human microarray datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.