GEO series
Multiomic profiling of vascular endothelial cell differentiation from human embryonic stem cells
GSE201709
Homo sapiens
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
130 samples
2026/05/30
GPL28038GPL20301
Summary
To investigate gene regulatory dynamics of normal endothelial cell (EC) differentiation at high resolution, an in vitro differentiation system was employed to derive functional vascular ECs from human embryonic stem cells. Human embryonic stem cells, mesodermal cells, and differentiating cells following VEGF-A stimulation at eight time points (1–48 hours), along with internal controls without VEGF-A treatment (referred to as non-ECs), were collected to profile global RNA expression and H3K27ac signals. In addition, in situ Hi-C data were generated for ECs and non-ECs at 24 hours after VEGF-A treatment to characterize global chromatin contact profiles associated with the EC progenitor state.
Download
NCBI GEO page ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
human RNA-seq datasets →
Similar datasets
- GSE301719 Mezigdomide reverses T cell exhaustion through degradation of Aiolos/Ikaros and reinvigoration of cytokine production pathways 74 samples
- GSE283600 LINE-1 transposable elements regulate the exit of human pluripotency and early brain development 83 samples
- GSE313074 Repeat expansions in C9orf72 rewire the 3D chromatin landscape in ALS 39 samples
- GSE309515 Independent cell type-specific expression and distal regulation of the 9p21 locus cell cycle regulators: p14ARF, p16INK4A, p15INK4A, and ANRIL 72 samples
- GSE293136 Multimodal remodeling of epigenetic and enhancer networks shapes the transcriptional landscape of beige adipocytes 66 samples
- GSE241691 Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2 59 samples
- GSE281522 Landscape of the Epstein-Barr virus-host chromatin interactome and gene regulation 41 samples
- GSE223639 Estrogen-induced NETs promote aseptic inflammation via NKCC1 [human] 34 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.