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Next-generation RNA Sequencing and Transcriptome Comparison of Mouse Wild Type and Mesenchymal Bmpr1a conditional knockout lungs of E15.5

GSE97946 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/04/01 Platform GPL19057
Summary
Lung mesenchymal knockout of Bmpr1a will lead to lung malformation, including impaired lung branching and cystic lesion. In order to understand the underlying mechanisms, total RNA of wild type and mesenchymal Bmpr1a knockout lungs were isolated and sequenced using the next-generation RNA sequencing technique.
Published in
Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts
Luo Y, Cao K, Chiu J et al. · eLife 2024 · PMID 38856718 · doi:10.7554/eLife.91876
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Also filed as BioProject PRJNA383414 and SRA study SRP104193. Searching any of these in the dataset finder brings you back here.

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