Drug, across the briefings

Sorafenib across 5 cancers

Sorafenib appears in 5 of the briefings; its FDA label names 1 of those diseases.

DiseaseFDA labelOpen Targets stage, on which geneTrialsActive
Hepatocellular carcinomalabel names diseaseapproved on KDR17511
Acute myeloid leukemiaapproved on FLT3, KIT5315
Colorectal cancerapproved on BRAF190
Lung cancerapproved on BRAF, RET440
Melanomaapproved on BRAF, KIT301

The label column is the briefing's openFDA stage: a label whose Indications and Usage names the disease. The Open Targets column is the furthest clinical stage recorded for the drug against any gene on that briefing's target list, in any indication. Trials are ClinicalTrials.gov interventional studies naming the drug and the disease, from the briefing's trials stage; a dash means the briefing did not search this drug in that disease (it searches the drugs Open Targets lists against its own genes), which is not the same as none. Salt forms, biosimilar suffixes and formulation words are merged by the same rule the briefings use.