Target, across the briefings

PIK3CD across 2 cancers

PIK3CD is on the target list of 2 of the briefings. A drug aimed at it carries an FDA label naming the disease in 2, and is approved for some indication in 2.

DiseaseLabel statusFurthest stage (Open Targets)Distinct drugsCell-therapy trials
Chronic lymphocytic leukemiaapproved here Duvelisib, Idelalisibapproved42
Follicular lymphomaapproved here Idelalisibapproved420 via PI3K

"Approved here" means a drug Open Targets records as aimed at PIK3CD carries an FDA label that names that disease, per the briefing's openFDA stage. "Approved elsewhere" means the drug is approved for some other indication. Stage is the furthest Open Targets clinical stage among drugs aimed at the gene, in any indication; the database is reported as it is, and it lags some approvals. Cell-therapy trials are counted on the antigen the briefing maps the gene to, from ClinicalTrials.gov.