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Chip-chip from mouse embryonic stem (mES) cells

GSE11329 Mus musculus Genome binding/occupancy profiling by genome tiling array 14 samples Submitted 2008/05/06 Platform GPL5811
Summary
To understand how pluripotency is controlled, we employed a modification of standard ChIP-chip method (biotin-mediated ChIP-chip) to identify targets of nine factors, including somatic cell reprogramming factors (Oct4, Sox2, Klf4, c-Myc) and others (Nanog, Dax1, Rex1, Zpf281, and Nac1) in mouse ES cells. We show the application of In vivo biotinylation mediated ChIP (bioChIP) to global target mapping. Our data also show that differential regulation of target genes correlates with the extent of promoter occupancy by multiple factors in maintaining stem cell pluripotency. Keywords: Biotin-mediated Chip-chip, Antibody ChIP-chip, Mouse embryonic stem cells
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Also filed as BioProject PRJNA106653. Searching any of these in the dataset finder brings you back here.

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