Transcriptome analysis of pulmonary CCR2+ inflammatory monocytes challenged with Cryptococcus neoformans
RNA-seq (gene expression) · mouse · 3 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 3 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE122765_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA506250 and SRA study SRP169944. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 3 more — browse all 3 samples with per-sample file links →
- GSE331196 Single-cell RNA sequencing of pulmonary myeloid cells from mixed bone marrow chimeric mice infected with Cryptococcus neoformans gcs1 mutant 2 samples shares cryptococcus, neoformans, pulmonary
- GSE277303 Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis 42 samples shares ccr2, monocytes
- GSE251648 CCR1 and CCR2 co-expression on monocytes is nonredundant and delineates a distinct monocyte subpopulation. 20 samples shares ccr2, monocytes
- GSE251646 CCR1 and CCR2 co-expression on monocytes is nonredundant and delineates a distinct monocyte subpopulation. [RNA-Seq] 19 samples shares ccr2, monocytes
- GSE249242 B cells mediate lung ischemia-reperfusion injury by recruitment of CCR2+-classical monocytes via synergistic BCR-TLR4 signaling 3 samples shares ccr2, monocytes
- GSE268156 CCR2+ monocytes promote white matter injury and cognitive dysfunction after myocardial infarction 2 samples shares ccr2, monocytes
- GSE251647 CCR1 and CCR2 co-expression on monocytes is non-redundant and delineates a distinct monocyte subpopulation. [scRNA-Seq] 1 samples shares ccr2, monocytes
- GSE287392 PDE4B deficiency aids macrophage Trojan horses to transfer Cryptococcus neoformans into the brain 1 samples shares cryptococcus, neoformans
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.