RNA-seq analysis of immune responses from human blood monocyte dendritic cells from 3 donors stimulated with 5 pattern recognition receptor (PRR) ligands along with their pairwise and triplet combinations
RNA-seq (gene expression) · human · 242 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 242 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE134874_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA556670 and SRA study SRP216393. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 242 more — browse all 242 samples with per-sample file links →
- GSE277565 RNA sequencing of human monocyte-derived dendritic cells stimulated with CLEC10A ligand glycodendrimers in the presence of Pam3CysK4 24 samples shares stimulated, dendritic, monocyte
- GSE232769 Transcriptomic analysis of human naive B cells stimulated by CD40L, CpG, anti-IgM IgG, IL-4 or combinations 36 samples shares combinations, stimulated
- GSE245936 NK receptors replace CD28 as the dominant source of signal 2 for cognate recognition of cancer cells by TAA-specific effector CD8+ T cells 12 samples shares recognition, receptor
- GSE217996 Gene expression profile of human monocyte-derived macrophage stimulated with AGP, anti-CD74 antibody, and mycobacterium avium infaction 8 samples shares stimulated, monocyte
- GSE237240 Gene expression profile of human monocyte-derived macrophage stimulated with AGP, anti-CD74 antibody, CRP, and mycobacterium avium infaction. 8 samples shares stimulated, monocyte
- GSE261067 Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma 7 samples shares stimulated, receptor
- GSE262963 Transcriptional profile of human monocyte-derived macrophages stimulated with Interleukin 27 6 samples shares stimulated, monocyte
- GSE252034 Gene expression profile of human monocyte-derived macrophage stimulated with anti-CD74 antibody(10mg/mL). 3 samples shares stimulated, monocyte
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.