Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomics
Single-cell RNA-seq · mouse · 26 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Mus musculus (mouse)
- Samples
- 26 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE136103_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA561303 and SRA study SRP218975. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 26 more — browse all 26 samples with per-sample file links →
- GSE298435 Transcriptomic Characterization of Liver Tissue Changes in Human and Mice with Acute-on-Chronic Liver Failure and Liver Cirrhosis/Fibrosis 76 samples shares cirrhosis, liver
- GSE298719 A Human Single-cell Atlas Identifies OLR1+ Scar-associated Macrophages as a Therapeutic Target for Chronic Liver Disease 41 samples shares single-cell, liver
- GSE261742 Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens 69 samples shares single-cell, fibrotic
- GSE202126 Single-cell Total-RNA Profiling Unveils Regulatory Hubs of Transcription Factors 1089 samples shares single-cell
- GSE249011 Bulk and single-cell RNA sequencing of human and murine eosinophil lineage cells 62 samples shares single-cell
- GSE309745 Single-cell and single-nucleus transcriptomic profiling of mouse models and human lung tissues to study pulmonary fibrosis 54 samples shares single-cell
- GSE272618 Single-Molecule Barcoding Technology for Single-Cell Genomics 140 samples shares single-cell
- GSE331030 Lentiviral single-cell MPRA of synthetic enhancers reveals motif affinity-based encoding of cell state specificity [sc-lentiMPRA 2] 66 samples shares single-cell
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.