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Chromatin accessibility timecourse of Naïve to Th17 polarization in wildtype mouse CD4 T cells [ATAC-seq]

GSE157576 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 6 samples Submitted 2024/12/31 Platform GPL21103
Summary
We applied ATACseq technology for mapping chromatin accessibility during CD4+ T cells activation. Briefly, we generated genome-wide chromatin-state maps of naive, Th17 at 48 hours and 72 hours. Using a series of ATAC-seq timecourse experiment, we revealed that chromatin accessibility is dynamic between naive and Th17, especially at the Th17 singature gene loci. These open chromatin sites may function as important cis-regulate elements for cell-specific genes expression.
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Also filed as BioProject PRJNA661772 and SRA study SRP280291. Searching any of these in the dataset finder brings you back here.

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