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Chromatin accessibility profiling of high endothelial cells (HECs) from mouse peripheral lymph node and Peyer's patch by ATAC-seq

GSE342565 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 2 samples 2026/08/06 GPL37305
Summary
High endothelial venules (HEVs) are specialized blood vessels that mediate lymphocyte entry into secondary lymphoid organs. We performed ATAC-seq on high endothelial cells (HECs) isolated by flow cytometry from mouse peripheral lymph nodes (PLNs, identified by PNAd expression using the MECA-79 antibody) and Peyer's patches (PPs, identified by MAdCAM-1 expression using the MECA-367 antibody) to characterize genome-wide chromatin accessibility and identify HEC-specific cis-regulatory elements.
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